Anticancer peptide (ACP) is a class of anti-cancer peptide which can inhibit and kill tumor cells.
Independent Research as a Resident Physician: Novel Methods for Data Collection, Teaching, and Collaboration During Graduate Medical Training
.Identification of ACPs is of great significance for the development of new anti-cancer drugs.However, most of computational methods make predictions based on machine learning using hand-crafted features.
Environmental effect of conventional and GM crops of cotton (Gossipium hirsitum L.) and corn (Zea mays L.)
.
In this article, we propose a new graph learning based computational model, named ACP-GCN, to automatically and accurately predict ACPs based on graph convolution networks.In this model, we for the first time take the ACP prediction as a graph classification task, where each peptide sample is represented as a graph.The experimental results show that the proposed model outperforms most of state-of-the-art methods, demonstrating that the proposed method can effectively distinguish ACPs from non-ACPs.
The excellent predictive ability will rapidly push forward their applications in cancer therapy